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PGC-related gene variants and elite endurance athletic status in a Chinese cohort: a functional study.
He ZH, Hu Y, Li YC, Gong LJ, Cieszczyk P, Maciejewska-Karlowska A, Leonska-Duniec A, Muniesa CA, Marín-Peiro M, Santiago C, Garatachea N, Eynon N, Lucia A. He ZH, et al. Scand J Med Sci Sports. 2015 Apr;25(2):184-95. doi: 10.1111/sms.12188. Epub 2014 Feb 20. Scand J Med Sci Sports. 2015. PMID: 25170593
This study aims to examine the association between proliferator-activated receptor gamma (PGC)-gene family-related single nucleotide polymorphisms (SNPs) and elite endurance runners' status in a Chinese cohort, and to gain insights into the functionality of a subset of SNPs. Geno …
This study aims to examine the association between proliferator-activated receptor gamma (PGC)-gene family-related single nucleotide polymor …
PPRC1, but not PGC-1alpha, levels directly correlate with expression of mitochondrial proteins in human dermal fibroblasts.
Mori MP, Souza-Pinto NC. Mori MP, et al. Genet Mol Biol. 2020 Jul 3;43(1 suppl. 1):e20190083. doi: 10.1590/1678-4685-GMB-2019-0083. Genet Mol Biol. 2020. PMID: 32639509 Free PMC article.
Moreover, PGC1-alpha expression did not correlate with expression levels of TFAM and SDHA, known PGC-1alpha target-genes. In turn, PPRC1, another member of the PGC family of transcription co-activators controlling mitochondrial biogenesis, displayed a good correlati …
Moreover, PGC1-alpha expression did not correlate with expression levels of TFAM and SDHA, known PGC-1alpha target-genes. In turn, …
Mitochondrial DNA content, an inaccurate biomarker of mitochondrial alteration in human immunodeficiency virus-related lipodystrophy.
Kim MJ, Jardel C, Barthélémy C, Jan V, Bastard JP, Fillaut-Chapin S, Houry S, Capeau J, Lombès A. Kim MJ, et al. Antimicrob Agents Chemother. 2008 May;52(5):1670-6. doi: 10.1128/AAC.01449-07. Epub 2008 Mar 10. Antimicrob Agents Chemother. 2008. PMID: 18332166 Free PMC article.
However, the expression of the known transcription factors of mitochondrial biogenesis (TFAM, NRF1, GABPA, PPARGC1A, PPARGC1B, and PPRC1) was normal or decreased. ...
However, the expression of the known transcription factors of mitochondrial biogenesis (TFAM, NRF1, GABPA, PPARGC1A, PPARGC1B, and …
Alterations in the molecular control of mitochondrial turnover in COPD lung and airway epithelial cells.
Tulen CBM, van de Wetering C, Schiffers CHJ, Weltjens E, Benedikter BJ, Leermakers PA, Boukhaled JH, Drittij MJ, Schmeck BT, Reynaert NL, Opperhuizen A, van Schooten FJ, Remels AHV. Tulen CBM, et al. Sci Rep. 2024 Feb 27;14(1):4821. doi: 10.1038/s41598-024-55335-8. Sci Rep. 2024. PMID: 38413800 Free PMC article.
We observed significantly decreased transcript levels of key molecules controlling mitochondrial biogenesis (PPARGC1B, PPRC1, PPARD) in peripheral lung tissue from severe COPD patients. Interestingly, mRNA levels of the transcription factor TFAM (mitochondrial bioge …
We observed significantly decreased transcript levels of key molecules controlling mitochondrial biogenesis (PPARGC1B, PPRC1, PPARD) …